Elaine C Davis Selected Research

Cutis Laxa

6/2012	Alternative splicing and tissue-specific elastin misassembly act as biological modifiers of human elastin gene frameshift mutations associated with dominant cutis laxa.
9/2010	Mechanisms of emphysema in autosomal dominant cutis laxa.
6/2005	Autosomal dominant cutis laxa with severe lung disease: synthesis and matrix deposition of mutant tropoelastin.
5/2003	Domains in tropoelastin that mediate elastin deposition in vitro and in vivo.
1/2002	Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo.

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Elaine C Davis Research Topics

Disease

5	Aneurysm (Aneurysms) 11/2018 - 03/2005
5	Cutis Laxa 06/2012 - 01/2002
3	recessive Cutis laxa 07/2015 - 12/2006
3	Autosomal Dominant Cutis Laxa 06/2012 - 06/2005
3	Vascular System Injuries 01/2010 - 02/2005
2	Thoracic Aortic Aneurysm 01/2018 - 06/2017
2	Ascending Aorta Aneurysm 01/2018 - 10/2015
2	Osteogenesis Imperfecta (Lobstein Disease) 01/2013 - 04/2010
2	Emphysema 06/2011 - 09/2010
2	Pelvic Organ Prolapse 05/2011 - 01/2009
2	Marfan Syndrome (Marfan's Syndrome) 01/2011 - 12/2009
2	Thrombosis (Thrombus) 01/2010 - 08/2007
2	Supravalvular Aortic Stenosis (Aortic Supravalvular Stenosis) 12/2009 - 05/2003
2	Neointima 08/2007 - 02/2005
1	Rupture 01/2020
1	Blood Vessel Dissection 01/2020
1	Type IV Ehlers-Danlos Syndrome 01/2020
1	Fatty Liver 11/2018
1	Vascular Diseases (Vascular Disease) 06/2017
1	Aortic Dissection 06/2017
1	Gerodermia osteodysplastica 01/2014
1	Fibrosis (Cirrhosis) 11/2013
1	Systemic Scleroderma (Systemic Sclerosis) 11/2013
1	Inflammation (Inflammations) 10/2013
1	Airway Remodeling 10/2013
1	Neoplasms (Cancer) 03/2013
1	Contracture 01/2013
1	Abdominal Aortic Aneurysm 12/2012
1	Cardiovascular Abnormalities 03/2012
1	Sepsis (Septicemia) 01/2012
1	Wounds and Injuries (Trauma) 01/2012
1	Congenital contractural arachnodactyly 01/2011
1	Aortic Aneurysm (Aneurysm, Aortic) 09/2010
1	Brittle Bone Disorder 04/2010
1	Hypertension (High Blood Pressure) 12/2009
1	Carcinoma (Carcinomatosis) 04/2009
1	Prolapse 01/2009
1	Pulmonary Emphysema 06/2005
1	Bronchiectasis 06/2005
1	Lung Diseases (Lung Disease) 06/2005
1	Hernia (Hernias) 06/2005
1	Intellectual Disability (Idiocy) 03/2005
1	Acute-Phase Reaction 03/2005
1	Cleft Palate (Palate, Cleft) 03/2005
1	Craniosynostoses (Craniosynostosis) 03/2005
1	Congenital Heart Defects (Congenital Heart Defect) 03/2005
1	Vascular Remodeling 02/2005
1	Lung Injury 01/2005
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2005

Drug/Important Bio-Agent (IBA)

9	ElastinIBA 01/2018 - 05/2003
8	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2002
4	Fibrillin-1IBA 11/2013 - 12/2006
3	Peptide Hydrolases (Proteases)FDA Link 06/2011 - 01/2009
2	CollagenIBA 01/2020 - 01/2013
2	Extracellular Matrix ProteinsIBA 11/2018 - 01/2005
2	Actin Depolymerizing Factors (Cofilins)IBA 01/2018 - 10/2015
2	Transforming Growth Factor beta (TGF-beta)IBA 07/2015 - 03/2005
2	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2013 - 01/2005
2	Procollagen Type IIBA 01/2013 - 04/2010
2	TropoelastinIBA 09/2010 - 06/2005
1	KetonesIBA 11/2018
1	Biomarkers (Surrogate Marker)IBA 11/2018
1	fibulinIBA 11/2018
1	AcidsIBA 11/2018
1	Liver GlycogenIBA 11/2018
1	Protein Isoforms (Isoforms)IBA 06/2017
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2015
1	Angiotensin IIIBA 10/2015
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2015
1	Carrier Proteins (Binding Protein)IBA 07/2015
1	AutoantibodiesIBA 11/2013
1	CytokinesIBA 11/2013
1	IntegrinsIBA 11/2013
1	AllergensIBA 10/2013
1	OvalbuminIBA 10/2013
1	Collagen Type I (Type I Collagen)IBA 01/2013
1	ProcollagenIBA 01/2013
1	SmokeIBA 12/2012
1	EnzymesIBA 12/2012
1	Pancreatic Elastase (Elastase)IBA 12/2012
1	Biological ProductsIBA 06/2012
1	MorpholinosIBA 03/2012
1	Polymethyl Methacrylate (Sol)IBA 01/2012
1	Transcription Factors (Transcription Factor)IBA 01/2012
1	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 01/2012
1	Fibrillin-2IBA 01/2011
1	Mitogen-Activated Protein Kinase 3IBA 02/2010
1	Thromboplastin (Tissue Factor)IBA 01/2010
1	fibulin 2IBA 01/2010
1	Proton-Translocating ATPases (ATPase, H+)IBA 06/2009
1	Metalloproteases (Metalloproteinases)IBA 01/2009
1	Thrombospondin 1IBA 08/2007
1	Peptides (Polypeptides)IBA 06/2005
1	LigandsIBA 03/2005
1	ImmunophilinsIBA 01/2005
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2005

Therapy/Procedure

2	Ligation 01/2010 - 02/2005
1	Therapeutics 11/2013